Genetics confuses me. Luckily there are people out there who are much smarter and not confused by such things. Leave it to the people at the National Institute of Health to make discoveries.
An article came out today discussing some new research about the elevated level of tryptase in the blood contributing to many of the dysautonomia symptoms. Tryptase is a type of protein and the elevations are due to multiple copies of an Alpha Tryptase gene.
Previous studies had shown that approximately 4-6% of the general public has high tryptase levels, however not all of those people experienced these well-known to me dysautotnomia symptoms.
I know there have always been questions about whether or not POTS is hereditary. In this research study 35 families were studied and it was confirmed that all affected members had inherited multiple copies of the alpha tryptase gene. The scientists also found that those who reported worse symptoms had three copies of the gene and the subjects who had less symptoms only had two copies of the gene.
Naturally, I now am curious about my genes and how many copies I have.
There is a reason I’m taking the time to paraphrase all of these big medical words for you. I think we should be encouraged by this study. If someone is looking into it at all, their goal is knowledge which inevitably leads to answers. Knowledge really is power.
The senior author of the study, Dr. Joshua Milner, was quoted saying, ““If we can devise a way to block alpha tryptase, we might be able to alleviate some or all of the symptoms related to elevated tryptase levels.”
Dr. Joshua Milner, you are welcome to come over for dinner!
P.S. If you could go ahead and find a way to make my levels of tryptase in my blood be reduced, therefore stopping my POTS symptoms, I’d be eternally grateful. I’ll even make you a peach pie.
Here’s a video explanation.
Here is a link to the article if you’d like to read it for yourself!